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These beneficial effects manifested with altered gene expression, including genes that increased ( Egr, Nos3, Srf, and Kras ) and genes that decreased ( Egr1, Vegfr2, and Plcɣ ), while Akt1 remained unchanged in the inferior caval vein, the right ovarian vein and the left ovarian vein (Vukojevic et al., 2018)
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This triad may be the focus of early therapies that delay neurodegeneration
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